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🏈 NFL AI Picks, Predictions and Model Probabilities

Our NFL picks are built using predictive systems that combine team performance metrics, quarterback play, and matchup data. We analyze offensive and defensive strengths to generate high-confidence predictions for spreads, totals, and moneyline outcomes.
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📅 2026-09-17 TODAY
🏈 NFL 8:15 PM ET
Detroit Lions
Sharp Consensus
36.9%
Books Est. +133
Prediction Lab +161
@
Buffalo Bills
Sharp Consensus
63.1%
Books Est. -161
Prediction Lab -191
Books spread
Buffalo Bills -3
Books total
O/U 52.5
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Analysis ▾
Injuries
⚠ Lions: I. Pacheco (back) — Injured Reserve ⚠ Lions: C. Mays (wrist) — Injured Reserve ⚠ Lions: P. Turner — Injured Reserve ⚠ Bills: T. Shavers — Out ⚠ Bills: D. Strong — Out
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