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🏈 NFL AI Picks, Predictions and Model Probabilities

Our NFL picks are built using predictive systems that combine team performance metrics, quarterback play, and matchup data. We analyze offensive and defensive strengths to generate high-confidence predictions for spreads, totals, and moneyline outcomes.
Showing picks for 2026-09-21. View today's picks →
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📅 2026-09-21
🏈 NFL 8:15 PM ET
New York Giants
Sharp Consensus
12.2%
Books +370
Prediction Lab +688
@
Los Angeles Rams
Sharp Consensus
87.8%
Books -485
Prediction Lab -1000
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Analysis ▾
Injuries
⚠ Rams: M. Garrett (knee) — Injured Reserve
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